TY  - CHAP
U1  - Konferenzveröffentlichung
A1  - Laubender, Elmar
A1  - Matylitskaya, Volha
A1  - Kostal, Elisabeth
A1  - Kasemann, Stephan
A1  - Urban, Gerald A.
A1  - Partel, Stefan
A1  - Dincer, Can
T1  - Gold nanogap interdigitated arrays for redox cycling amplified dopamine detection
T2  - 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII). 23-27 June. Berlin. Germany
N2  - Here we present the highly sensitive detection of dopamine using gold nanogap IDAs with redox-cycling amplification. Through the combination with a facile electrochemical activation and a chronoamperometric multistep protocol fouling of the gold electrode surface can be prevented and a sensitivity of 14 nA μM -1 with excellent linearity up to 10 μM is achieved. The low-cost and reproducible wafer level fabrication process of the nanogap IDAs plays a key role. Electrode and substrate materials can be nearly arbitrarily chosen. Also the gap sizes could be adjusted down to sub-100 nm dimensions with this versatile approach, allowing for very high signal amplification. In comparison to the current gold standard, fastscan cyclic voltammetry (FSCV) with carbon fiber microelectrodes (CFMEs), which suffers from high background currents, no elaborate data processing and high-end electronic equipment is needed. Employing our flexible, easy and inexpensive method, DA monitoring with a short acquisition period and a detection limit less than 200 nM is successfully demonstrated.
KW  - Electrodes
KW  - Gold
KW  - Electric potential
KW  - Protocols
KW  - Fingers
KW  - Sensitivity
KW  - Monitoring
Y1  - 2019
SN  - 978-1-7281-2007-2
SB  - 978-1-7281-2007-2
U6  - https://doi.org/10.1109/TRANSDUCERS.2019.8808356
DO  - https://doi.org/10.1109/TRANSDUCERS.2019.8808356
SP  - 1017
EP  - 1020
PB  - IEEE
CY  - Danvers, MA
ER  -