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In this work, we present a significant step toward in vivo ophthalmic optical coherence tomography and angiography on a photonic integrated chip. The diffraction gratings used in spectral-domain optical coherence tomography can be replaced by photonic integrated circuits comprising an arrayed waveguide grating. Two arrayed waveguide grating designs with 256 channels were tested, which enabled the first chip-based optical coherence tomography and angiography in vivo three-dimensional human retinal measurements. Design 1 supports a bandwidth of 22 nm, with which a sensitivity of up to 91 dB (830 µW) and an axial resolution of 10.7 µm was measured. Design 2 supports a bandwidth of 48 nm, with which a sensitivity of 90 dB (480 µW) and an axial resolution of 6.5 µm was measured. The silicon nitride-based integrated optical waveguides were fabricated with a fully CMOS-compatible process, which allows their monolithic co-integration on top of an optoelectronic silicon chip. As a benchmark for chip-based optical coherence tomography, tomograms generated by a commercially available clinical spectral-domain optical coherence tomography system were compared to those acquired with on-chip gratings. The similarities in the tomograms demonstrate the significant clinical potential for further integration of optical coherence tomography on a chip system.
Towards a high productivity automatic analysis framework for classification. An initial study
(2013)
Towards a novel infrastructure for conducting high productive cloud-based scientific analytics
(2016)
Towards a strategic management framework for engineering of organizational robustness and resilience
(2020)
Data is the new oil,” said British Mathematician and Tesco marketing mastermind Clive Humbly1. Data has also been described as the backbone of digital retail enterprises2 and the currency of the digital age. Whether these statements live up to be true is debatable, but what is certain is the fact that the internet age has contributed to the avalanche of data witnessed today. In a century dominated by predictive analysis and artificial intelligence, it is no surprise that by the end of the last decade, data companies Apple, Amazon and Microsoft closed as the world´s first trillion-dollar companies, with their revenues dwarfing economies of several countries across the globe.3The recognition of the importance of data in today´s economy bears with it the responsibility to protecting its owners. While this intricate balance has long been the subject of legal analysis the General Data Protection Regulation, 2018, is hailed as the world´s most comprehensive and strict data protection regime currently in force. In addition to protecting the personal data of persons from its member countries, the Regulation also seeks to ensure the same protection accompanies any data transferred out of the European Union to other countries. It is almost 5 years since the Regulation was passed and process of implementation into business operations an important topic of discussion. Of importance to this study are the Modernized Standard Contractual Clauses, a tool of data transfer to countries outside the EU, which replace the three sets of SCCs adopted by the now repealed Data Protection Directive 94/46. These Standard Contractual Clauses came into effect on 27th September 2021, and companies have until 27th September 2022 to rely on the old set of clauses. With this deadline coming up, how far have the clauses been integrated into operations by businesses in Austria and the EU?
Transparent laser-structured glasses with superhydrophilic properties for anti-fogging applications
(2019)
Ultrashort pulse laser structuring enables direct modification of glass surfaces to generate superhydrophilic properties for anti-fogging applications. This approach makes coatings dispensable and the generated surfaces remain thermally, mechanically, and chemically resistant. However, the laser-generated structures usually cause scattering, which decreases transmission and may disturb the vision through the modified glass in the dry state. The aim of this study was to find a laser-processing strategy to achieve superhydrophilic, anti-fogging properties on glass surfaces with maximum transmission and minimal visual perception of the generated structure. For this purpose, we used an ultrashort-pulsed laser to generate periodic patterns of rippled circles or rough holes with varying pitch. The water contact angle and transmission of the structured glasses were measured as a function of the structured area. It was found that a periodic pattern of holes, which covers less than 1% of the surface, is already sufficient to reach the superhydrophilic state (contact angle < 5°) and provides nearly the same transmission as pristine glass. Pictures of objects imaged through dry, structured glasses, which were placed close to the lens or object, showed in both cases only a minimal decrease of contrast. If this minor drawback can be accepted, this direct laser structuring approach could be an interesting alternative to coating-based techniques and leaves even room to apply additional coatings for the fabrication of multi-functional special glasses.
The e-commerce market has been growing for years and this trend seems to be continuing. Online stores for clothing are very successful. It seems that hardly any company can afford not to have a digital presence. This goes hand in hand with the fact that the range of products on offer to customers is getting bigger and bigger. But it's not just the range that's getting bigger, it's also the effort customers have to make to find the right product. For this reason, many successful online stores are already relying on AI. In doing so, companies are creating opportunities for customers that an employee could hardly manage. Implemented on the website, AI can check inventory, update it in real time, predict trends and evaluate customer or user data and make suitable recommendations. This is important for the customer because with the huge choice available, for one thing, personalization is increasingly important and being presented with a relevant selection. A central question is whether the recommendations are trustworthy and whether they can be equated with a real salesperson advising the customer. After all, trust is relevant in longterm customer relationships in that it leads to loyalty and satisfaction, which in turn increases the intention to repurchase. The recommendation tools mentioned are also of particular interest for another reason. On the one hand, they help customers to get a relevant selection of the offer and thus to get faster to the desired one. On the other hand, they are relevant for companies not only because of customer satisfaction, but also because of the chance to reduce returns. The large online stores for clothing offer their customers very generous opportunities to return the goods free of charge. In doing so, the companies have responded to customer wishes, because hardly anything is more important to them when it comes to online shopping: free returns. In this way, customers have minimized the risk of having to keep goods that do not fit or please them. This thesis examines whether recommendation tools can help customers to better assess the sizes and properties of clothing, so that they receive more suitable clothing and do not even feel the need to order several sizes of the same item of clothing. It can therefore be assumed that trust in the recommendations of the AI tools reduces uncertainty, which in turn should reduce the intention to return goods. Another assumption to be tested is that of the perceived usefulness of the recommendation tools. As a prerequisite to get an assessment of these assumptions is the usage of the tools. Therefore, a survey was initiated in the DACH region to assess the extent to which usage influences the factors mentioned. It was found by means of a regression analysis that the frequency of online purchases, mediated by perceived usefulness, explains the influence on trust.