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By a simple femtosecond laser process, we fabricated metal-oxide/gold composite films for electrical and optical gas sensors. We designed a dripple wavelength AWG-spectrometer, matched to the plasma absorption wavelength region of the composite films. H2/CO absorptions fit well with the AWG design for multi gas detection sensor arrays
Why do some countries assign a major role to wind energy in decarbonizing their electricity systems, while others are much less committed to this technology? We argue that processes of (de-)legitimation, driven by discourse coalitions who strategically employ certain storylines in public debates, provide part of the answer. To illustrate our approach, we comparatively investigate public discourses surrounding wind energy in Austria and Switzerland, two countries that differ strongly in wind energy deployment. By combining a qualitative content analysis and a discourse network analysis of 808 newspaper articles published 2010–2020, we identify four distinct sets of storylines used to either delegitimize or legitimize the technology. Our study indicates that low deployment rates in Switzerland can be related to the prominence of delegitimizing storylines in the public discourse, which result in a rather low socio-political acceptance of wind energy. In Austria, by contrast, there is more consistent support for wind energy by discourse coalitions using a broad set of legitimizing storylines. By bridging the related but separate literatures of technology legitimacy and social acceptance, our study contributes to a better understanding of socio-political conflict and divergence in low-carbon technological pathways.
Long-Term outcome of infantile onset pompe disease patients treated with enzyme replacement therapy
(2024)
Background: Enzyme replacement therapy (ERT) with recombinant human alglucosidase alfa (rhGAA) was approved in Europe in 2006. Nevertheless, data on the long-term outcome of infantile onset Pompe disease (IOPD) patients at school age is still limited.
Objective: We analyzed in detail cardiac, respiratory, motor, and cognitive function of 15 German-speaking patients aged 7 and older who started ERT at a median age of 5 months.
Results: Starting dose was 20 mg/kg biweekly in 12 patients, 20 mg/kg weekly in 2, and 40 mg/kg weekly in one patient. CRIM-status was positive in 13 patients (86.7%) and negative or unknown in one patient each (6.7%). Three patients (20%) received immunomodulation. Median age at last assessment was 9.1 (7.0–19.5) years. At last follow-up 1 patient (6.7%) had mild cardiac hypertrophy, 6 (42.9%) had cardiac arrhythmias, and 7 (46.7%) required assisted ventilation. Seven patients (46.7%) achieved the ability to walk independently and 5 (33.3%) were still ambulatory at last follow-up. Six patients (40%) were able to sit without support, while the remaining 4 (26.7%) were tetraplegic. Eleven patients underwent cognitive testing (Culture Fair Intelligence Test), while 4 were unable to meet the requirements for cognitive testing. Intelligence quotients (IQs) ranged from normal (IQ 117, 102, 96, 94) in 4 patients (36.4%) to mild developmental delay (IQ 81) in one patient (9.1%) to intellectual disability (IQ 69, 63, 61, 3x < 55) in 6 patients (54.5%). White matter abnormalities were present in 10 out of 12 cerebral MRIs from 7 patients.
Objectives: The MetabQoL 1.0 is the first disease-specific health related quality of life (HrQoL) questionnaire for patients with intoxication-type inherited metabolic disorders. Our aim was to assess the validity and reliability of the MetabQoL 1.0, and to investigate neuropsychiatric burden in our patient population. Methods: Data from 29 patients followed at a single center, aged between 8 and 18 years with the diagnosis of methylmalonic acidemia (MMA), propionic acidemia (PA) or isovaleric acidemia (IVA), and their parents were included. The Pediatric Quality of Life Inventory (PedsQoL) was used to evaluate the validity and reliability of MetabQoL 1.0.
Results: The MetabQoL 1.0 was shown to be valid and reliable (Cronbach's alpha: 0.64–0.9). Fourteen out of the 22 patients (63.6%) formally evaluated had neurological findings. Of note, 17 out of 20 patients (85%) had a psychiatric disorder when evaluated formally by a child and adolescent psychiatrist. The median mental scores of the MetabQoL 1.0 proxy report were significantly higher than those of the self report (p = 0.023). Patients with neonatal-onset disease had higher MetabQoL 1.0 proxy physical (p = 0.008), mental (p = 0.042), total scores (p = 0.022); and self report social (p = 0.007) and total scores (p = 0.043) than those with later onset disease.
Conclusions: This study continues to prove that the MetabQoL 1.0 is an effective tool to measure what matters in intoxication-type inherited metabolic disorders. Our results highlight the importance of clinical assessment complemented by patient reported outcomes which further expands the evaluation toolbox of inherited metabolic diseases.
Zu Beginn wurde im eigenen beruflichen Umfeld beobachtet, dass Informationen und Wissen, die heutzutage im Arbeitsalltag in Fülle ausgetauscht werden, häufig nicht die gewünschte Aufmerksamkeit und Offenheit erhalten. Diese Masterarbeit untersucht, wie bei dieser Art von Beobachtungen, deren komplexe Natur die Identifizierung von Lösungsansätzen erschwert, das eigentliche Problem erkannt werden kann. Frederic Vester zufolge ermöglicht ein vernetztes Denken dabei, Erkenntnisse vor allem aus den miteinander verknüpften Faktoren zu gewinnen. Diese Denkweise lässt sich in einer systemischen wie auch einer transdisziplinären Betrachtungsweise finden, wobei diese der Herausforderung gegenüberstehen vielfältige Perspektiven auf das Problem miteinander in Einklang zu bringen. Dies wirft die Frage auf, inwiefern eine gestalterische Zwischeninstanz dazu beitragen kann, einen gemeinsamen Denkraum zu eröffnen. Das Ziel dieser Arbeit ist, einen Entwurfsvorschlag für die Gestaltung eines Erkenntnisprozesses zu erarbeiten. Der Forschungsansatz dieser Arbeit – (FÜR+ÜBER)DURCH – leitet sich aus Christopher Fraylings Kategorien zur Designforschung ab. Die ‚Recherche FÜR‘ führt dazu, ein Problem als ein System zu betrachten, für das Wolfgang Jonas ein Problem-Design vorschlägt. In der ‚Recherche ÜBER‘ zeigt sich, dass es explizites wie auch implizites Wissen für eine umfassende Problembetrachtung braucht. Dafür wurde die Spuren-sicherung der Kunst auf das Design übertragen, um vorhandenes Wissen visuell zu dokumentieren. Mit Charles S. Peirce visuelles Entwurfs- und Erkenntnisverfahren lässt sich zudem ein anschauliches Denken durch diagrammatisches Schlussfolgern fördern. Die theoretischen Erkenntnisse münden in der ‚Transformation DURCH‘ in einen Vorschlag für ein diagrammatisches Problem-Design. Diesen gilt es in Bezug zu dem praxisbasierten Gestaltungsentwurf aus dem Masterprojekt zu reflektieren. In einer Werkshalle wurden Prototypische Beobachtungen zum ‚Zusammenspiel von Aufmerksamkeit und Offenheit‘ physisch in Beziehung gesetzt und anschließend mit zwei Testgruppen daraufhin untersucht, ob sich daraus neue Erkenntnisse ergeben. Es zeigte sich, das Design auf diese Weise einen gemeinsamen Austausch fördern kann. Gleichzeitig wurde deutlich, dass der Gestaltungsprozess die Vernetztheit eines Problems darstellen kann, jedoch ein vernetztes Denken aktiv initiiert werden muss, wofür im Entwurfsvorschlag dieser Arbeit ein visuelles Verfahren vorgestellt wird.
In this paper, we consider the question of data aggregation using the practical example of emissions data for economic activities for the sustainability assessment of regional bank clients. Given the current scarcity of company-specific emission data, an approximation relies on using available public data. These data are reported in different standards in different sources. To determine a mapping between the different standards, an adaptation to the Covariance Matrix Self-Adaptation Evolution Strategy is proposed. The obtained results show that high-quality mappings are found. Nevertheless, our approach is transferable to other data compatibility problems. These can be found in the merging of emissions data for other countries, or in bridging the gap between completely different data sets.
This study presents different approaches to increase the sensing area of NiO based semiconducting metal oxide gas sensors. Micro- and nanopatterned laser induced periodic surface structures (LIPSS) are generated on silicon and Si/SiO2 substrates. The surface morphologies of the fabricated samples are examined by FE SEM. We select the silicon samples with an intermediate Si3N4 layer due to its superior isolation quality over the thermal oxide for evaluating the hydrogen and acetone sensitivity of a NiO based test sensor.
Daten im B2B-Ökosystem teilen und nutzen: Wie KMU Voraussetzungen schaffen und Hürden überwinden
(2024)
«Big Data» haben ein großes Potenzial, um die Wertschöpfung effizienter zu gestalten oder um Innovationen hervorzubringen. Daten werden oft an der Schnittstelle zwischen mehreren Akteuren in Business-to-Business-Ökosystemen generiert und sie müssen zwischen den Akteuren geteilt werden. Unternehmen tun sich jedoch schwer damit, Daten in Werte zu transferieren und die Daten im Ökosystem zu teilen. Ursächlich sind weniger technische Gründe als organisationale Rahmenbedingungen. Der Beitrag identifiziert fünf Perspektiven, die Hürden und Voraussetzungen in diesem Prozess darstellen: (1) eine datengetriebene Organisationskultur, (2) Vertrauen zwischen den Akteuren, (3) die Konkretisierung des Wertes von Daten, (4) Datensicherheit und (5) rechtliche und Governance-Aspekte. Eine Fallstudie eines typischen Daten-Ökosystems um ein produzierendes KMU konkretisiert diese Voraussetzungen und Hürden. Es zeigt sich, dass sich Unternehmen, die Daten im Ökosystem teilen möchten, ganzheitlich verändern müssen.
Das Konzept der entscheidungsgetriebenen Organisation basiert auf der Tatsache, dass jede Aktivität entlang der arbeitsteiligen Wertschöpfung in einer Organisation1 im Kern auf Entscheidungen beruht, die aneinander anknüpfen.2 Jede Aktivität kann man vollziehen oder unterlassen, beide Möglichkeiten sind zunächst gleichgewichtig. Jede argumentative Begründung für eine Aktivität ist dabei zugleich eine Begründung gegen alle anderen, ebenso möglichen Aktivitäten. Da dies für alle wertschöpfenden Aktivitäten in einer Organisation gilt, werden Entscheidungen von jeder an der arbeitsteiligen Leistungserstellung beteiligten Person getroffen.
The utilization of lasers in dentistry expands greatly in recent years. For instance, fs-lasers are effective for both drilling and caries prevention, while cw-lasers are useful for adhesive hardening. A cutting-edge application of lasers in dentistry is the debonding of veneers. While there are pre-existing tools for this purpose, there is still potential for improvement. Initial efforts to investigate laser assisted debonding mechanisms with measurements of the optical and mechanical properties of teeth and prosthetic ceramics are presented. Preliminary tests conducted with a laser system used for debonding that is commercially available showed differences in the output power set at the systems console to that at specified distances from the handpiece. Furthermore, the optical properties of the samples (human teeth and ceramics) were characterised. The optical properties of the ceramics should closely resemble those of teeth in terms of look and feel, but they also influence the laser assisted debonding technique and thus must be taken into account. In addition first attempts were performed to investigate the mechanical properties of the samples by means of pump-probe-elastography under a microscope. By analyzing the sample surface up to 20 ns after a fs-laser pulse impact, pressure and shock waves could be detected, which can be utilized to determine the elastic constants of specific materials. Together such investigations are needed to shape the basis for a purely optical approach of debonding of veneers utilizing acoustic waves.
Open tracing tools
(2023)
Background: Coping with the rapid growing complexity in contemporary software architecture, tracing has become an increasingly critical practice and been adopted widely by software engineers. By adopting tracing tools, practitioners are able to monitor, debug, and optimize distributed software architectures easily. However, with excessive number of valid candidates, researchers and practitioners have a hard time finding and selecting the suitable tracing tools by systematically considering their features and advantages. Objective: To such a purpose, this paper aims to provide an overview of popular Open tracing tools via comparison. Methods: Herein, we first identified 30 tools in an objective, systematic, and reproducible manner adopting the Systematic Multivocal Literature Review protocol. Then, we characterized each tool looking at the 1) measured features, 2) popularity both in peer-reviewed literature and online media, and 3) benefits and issues. We used topic modeling and sentiment analysis to extract and summarize the benefits and issues. Specially, we adopted ChatGPT to support the topic interpretation. Results: As a result, this paper presents a systematic comparison amongst the selected tracing tools in terms of their features, popularity, benefits and issues. Conclusion: The result mainly shows that each tracing tool provides a unique combination of features with also different pros and cons. The contribution of this paper is to provide the practitioners better understanding of the tracing tools facilitating their adoption.
Das Forschungsprojekt Data Sharing Framework untersuchte Data Sharing im Kontext von datenbasierten Services und Produkten in Ökosystemen aus fünf Perspektiven: Kultur, Vertrauen, Wert, Recht & Governance, Sicherheit. Die Forschungsergebnisse bestätigen die Relevanz dieser Perspektiven und es hat sich gezeigt, dass diese Aspekte sowohl Barrieren als auch Treiber für Datennutzung und -austausch zwi- schen Unternehmen darstellen.
Ausgangspunkt waren die folgenden forschungs- und praxisleitenden Annahmen:
• These 1: KMU können durch die Nutzung und das
Teilen von Daten Mehrwerte in Form neuer Produkte und Services generieren. Aus wissenschaftlicher Sicht liegt der Fokus des Themas Daten und Data Science bisher überwiegend auf der technischen Umsetzung datenintensiver Geschäftsmodelle und Kooperationen durch die Unternehmen.
• These 2: Die technische Umsetzung ist eine notwendige Bedingung für die datenbasierte Leistun- gen, sie reicht jedoch nicht aus, um eine Kooperations- und Teilbereitschaft bei KMU hinsichtlich ihrer Daten (Daten-Teilbereitschaft) auszulösen. Zahlreiche Stakeholder zögern, Daten zu teilen, vor allem in einem grenzüberschreitenden Kontext, wie z.B. in der Programmregion.
• These 3: KMU benötigen Data Access und Data Trust Strukturen, um mögliche Kooperationspotenziale tatsächlich zu heben. Dies erfordert u.a. gemeinsa- me Standards, ein annäherndes Verständnis vom Wert der Daten, Data-Governance in Kombination mit zu definierenden Trust-Standards, welche die erforderliche formelle und informelle Sicherheit bieten.
Nachfolgend wird ein Überblick über die hieraus hervorgegangenen Ergebnisse gegeben:
Kultur
Die Perspektive der Organisationskultur stellt das Denken und Handeln im Unternehmen und im Ökosystem in den Mittelpunkt. Eine Organisationskultur, welche die Arbeit mit Daten, Data Science Praktiken und vor allem das Teilen von Daten ermöglicht, stellt Daten in den Mittelpunkt des Wertschöpfungsprozesses. Dies erfordert eine generelle Sensibilisierung
für das Thema Daten, durchlässige Grenzen im und zwischen Unternehmen, ebenso wie ein neues Verständnis von Rollen, Strukturen und Prozessen im Unternehmen.
Vertrauen
Das Vertrauen ist im Ökosystem von großer Bedeutung. Das Einbeziehen von internen Stakeholdern und das Starten mit kleineren Pilotprojekten wird vorgeschlagen, um Vertrauen innerhalb der Organisation und mit externen Partnern zu schaffen.
Wert
Als notwendige Voraussetzung wird der Wert der Daten hervorgehoben. Unternehmen sollten den potenziellen Wert der Datenflüsse kennen, bevor sie sich entscheiden, ob sie diese Daten teilen und nutzen möchten. Es wird empfohlen, eine grobe Quanti- fizierung des Wertflusses vorzunehmen oder gegebe- nenfalls eine detailliertere Analyse durchzuführen.
Recht & Governance
Für die Berücksichtigung rechtlicher Rahmenbedingungen gemeinsamer Datennutzung sollten Organisationen zunächst eine interne Data Governance etablieren, um auf neue regulatorische Entwicklungen reagieren zu können. Die Einrichtung von Data-Asset-Management, Data-IP und -Compliance-Ma-nagement und Data-Contract-Management wird hier empfohlen.
Datensicherheit
Im Sicherheitskontext sind Methoden zur Gewährleistung der Datenintegrität, Privatsphäre und Sicherheit entscheidend. Es wird empfohlen, einen kollaborativen Ansatz zur Implementierung von Sicherheitsstandards zu verfolgen und dabei IKT-Experten einzubeziehen. Anfänglich können Best Practices ausreichen, aber längerfristig sollte eine kontinuierliche Sicherheitsrisikobewertung und Ge- schäftsprozessintegration angestrebt werden.
Creating a schedule to perform certain actions in a realworld environment typically involves multiple types of uncertainties. To create a plan which is robust towards uncertainties, it must stay flexible while attempting to be reliable and as close to optimal as possible. A plan is reliable if an adjustment to accommodate for a new requirement causes only a few disruptions. The system needs to be able to adapt to the schedule if unforeseen circumstances make planned actions impossible, or if an unlikely event would enable the system to follow a better path. To handle uncertainties, the used methods need to be dynamic and adaptive. The planning algorithms must be able to re-schedule planned actions and need to adapt the previously created plan to accommodate new requirements without causing critical disruptions to other required actions.
Coupling is one of the most frequently mentioned metric in software systems. However, to measure logical coupling between microservices, runtime information is needed or the availability of service-log files to analyze the calls between services is required. This work presents our emerging results, in which we propose a metric to statically calculate logical coupling between microservices based on commits to versioning systems. We performed an initial validation of the proposed metric with a dataset containing 145 open-source microservices projects. The results illustrate how logical coupling affects every system and increases overtime. However, we did not find a correlation between the number of commits or the number of developers and the introduction of logical coupling. In future, we investigate why, how, and when logical coupling is introduced in a system.
This paper presents design, simulation, and optimization of the three-dimensional 1×4 optical multimode interference splitter using IP-Dip polymer as a core and polydimethylsiloxane (PDMS) Sylgard 184 as a cladding. The splitter was simulated by using beam propagation method in BeamPROP simulation engine of RSoft photonic tool and optimized for an operating wavelength of 1.55 µm. According to the minimum insertion loss, the dimensions of the MMI coupler and the length of the whole MMI splitter structure were optimized applying a waveguide with a core size of 4×4 µm2. The objective of the study is to create a design for fabrication by three-dimensional direct laser writing optical lithography.
Design, simulation, and optimization of the 1×4 optical three-dimensional multimode interference splitter using IP-Dip polymer as a core and polydimethylsiloxane (PDMS) Sylgard 184 as a cladding is demonstrated. The splitter was simulated by using beam propagation method in BeamPROP simulation module of RSoft photonic tool and optimized for an operating wavelength of 1.55 μm . According to the minimum insertion loss, the dimensions of the splitter were optimized for a waveguide with a core size of 4×4 μm2 . The objective of the study is to create the design for fabrication by three-dimensional direct laser writing optical lithography.
The role of entrepreneurs and intrapreneurs in the current zeitgeist is to drive innovation, re-shape rigid, established processes in business as well as for consumers. They use new viewpoints to pioneer new (business) models which focus on ‘smartness’ rather than the purely monetary and short-sighted models of yesteryear. Fostering and supporting the culture of this current zeitgeist is a mayor challenge for entre- and intrapreneurial support infrastructures, namely startup centres and innovation hubs of universities and other public institutions as well as innovation centres of private companies. Hereby, support may range from access to funding over provision of resources such as offices or computing hardware to coaching in the development of business ideas and strategic roadmaps for product and service deployment. In this paper, we focus on describing the status-quo of afore- mentioned support infrastructures in Vorarlberg and the Lake Constance region, then extend the scope to existing (international) approaches for aiding founders and inno- vators in the development of smart services. An analysis of success stories of the Vorarlberg startup centre ‘startupstube’ and other initiatives including their compar- ison to international counterparts builds the basis for a methodological framework for (service science) coaching in entre- and intrapreneurial support infrastructures. The paper is concluded by the description of a framework for choosing the right methods and tools to create service value in entre-/intrapreneurship based upon tested, proven know-how and for defining support infrastructure needs based upon pre-defined stakeholder and target groups as well as the (industry) sectors of the innovators.
International Entrepreneurship explains the opportunities and challenges facing internationalizing entrepreneurial ventures. The book inlcudes a thorough discussion of fundamentals as well as contemporary research findings. Numerous cases, featuring diverse contexts, illustrate theory and help classroom use.
Redundanz und Varietät
(2023)
Ausrechnen oder aushandeln?
(2023)
Vast amounts of oily wastewater are byproducts of the petrochemical and the shipping industry and to this day frequently discharged into water bodies either without or after insufficient treatment. To alleviate the resulting pollution, water treatment processes are in great demand. Bubble column humidifiers (BCHs) as part of humidification–dehumidification systems are predestined for such a task, since they are insensitive to different feed liquids, simple in design and have low maintenance requirements. While humidification in a bubble column has been investigated plentiful for desalination, a systematic investigation of oily wastewater treatment is missing in literature. We filled this gap by analyzing the treatment of an oil–water emulsion experimentally to derive recommendations for future design and operation of BCHs. Our humidity measurements indicate that the air stream is always saturated after humidification for a liquid height of only 10 cm. A residual water mass fraction of 3.5 wt% is measured after a batch run of six hours. Furthermore, continuous measurements show that an increase in oil mass fraction leads to a decrease in system productivity especially for high oil mass fractions. This decrease is caused by the heterogeneity of the liquid temperature profile. A lower liquid height mitigates this heterogeneity, therefore decreasing the heat demand and improving the overall efficiency. The oil content of the produced condensate is below 15 ppm, allowing discharge into various water bodies. The results of our systematic investigation prove suitability and indicate a strong future potential for the use of BCHs in oily wastewater treatment.
Purpose – The purpose of this study is to explore the exogenous and endogenous drivers of the high-growth of Unicorn start-ups along their life cycle, with a particular focus on Unicorns in the fintech industry.
Design/methodology/approach – The study employs an explorative longitudinal analysis with a matched pair of two cases of Unicorns start-ups with similar antecedent features to understand holistically drivers over the longer term.
Findings – High-growth patterns over the longer term are the result of a combined industry- and company-life cycle perspective. Drivers and growth patterns vary significantly according to the time of entry in the industry and
its development status. The findings are systematised within a set of propositions to be tested in future research.
Research limitations/implications – The limitations lie in empirical evidence, as the analysis is limited to one matched-pair. The revealed Unicorns’ drivers for long-term growth might encourage future research to further investigate these drivers on a larger scale.
Practical implications – The study offers practical recommendations for start-ups with high-growth ambitions and advice to policy makers regarding the development of tailor-made support programs.
Originality/value – The study significantly extends extant work on growth and high-growth by examining endogenous and exogenous triggers over time and by linking the Unicorn-life cycle to the industry life cycle, an approach which has, to the best of the authors’ knowledge, not yet been applied.
Digital twin as enabler of business model innovation for infrastructure construction projects
(2023)
Emerging technologies and methods are becoming an important element of the construction industry. Digital Twins are used as a base to store data in BIM models and make use out of the data respectively make the data visible. The transparency in all phases of the lifecycle of building and infrastructure assets is crucial in order to get a more efficient lifecycle of planning, construction and maintenance. Whereas other industries increased performance in these phases by making use out of the data, construction industry is stuck in traditional methods and business models. In this paper we propose a concept that focuses on the digital production twin. The comparison of planning data with As-Is production data can empower a data driven continuous improvement process and support the decision making process of future innovations and suitable business models. This paper outlines the possibility to use the data stored in a digital twin with regards to the evaluation of possible business models.
We present design of planar 16-channel, 100-GHz multi-mode polymer-based AWG. This AWG was designed for central wavelength of 1550 nm applying AWG-Parameters tool. The AWG structure was created and simulated in the commercial photonic tool PHASAR from Optiwave. Achieved transmission characteristics were evaluated by AWG-Analyzer tool. For the design, multi-mode waveguides having a cross-section of (4x4) µm2 were used. The simulated results show strong worsening of the transmission characteristics in comparison when using single-mode waveguides. Nevertheless, the transmitting channels are clearly separated. The reason for using thicker multi-mode waveguides in the design is possibility to fabricate the AWG structure on polymer basis using direct laser writing lithography.
Statistische Methodenkompetenz wird im Controlling zunehmend bedeutender, so ist die evidenzbasierte Prognose durch algorithmische Analyse von Datenbeständen ein Schwerpunkt von Controlling Analytics. Die Fallstudie durchleuchtet daher anhand von Datenmaterial des Schweizer Bundesamts für Statistik das Vorgehen bei einer Datenanalyse, insbesondere beim Einsatz der Zeitregression für Prognosezwecke, und geht dabei auf methodische Besonderheiten, Caveats und Einsatzmöglichkeiten in Microsoft Excel ein. Die Fallbeschreibung und Aufgaben sind im WiSt-Heft Nr. 4/23 zu finden.
Digitalization is changing business models and operational processes. At the same time, improved data availability and powerful analytical methods are influencing controlling and increasingly require the use of statistical and information technology skills and knowledge. Using a case study from marketing controlling, the article shows the use of business analytics methods and addresses the tasks of controlling in the digital age.
Optoelectronic system based on photonic integrated circuits to miniaturize spectral domain OCT
(2023)
We present a miniaturized optical coherence tomography (OCT) setup based on photonic integrated circuits (PIC) for the 850 nm range. We designed a 512-channel arrayed waveguide grating (AWG) on a PIC for spectral domain OCT (SD-OCT) that is co-integrated with PIN-photodiodes and analog-to-digital-converters on one single chip. This image sensor is combined with all the necessary electronics to act as a camera. It is integrated into a fiber-based OCT system, achieving a sensitivity of >80dB and various samples are imaged. This optoelectronic system will allow building small and cost-effective OCT systems to monitor retinal diseases.
Der vorliegende Beitrag stellt das Konzept eines Flipped Classroom-Ansatzes für die Lehrveranstaltung „Grundlagen der Wirtschaft und finanziellen Unternehmensführung“ im Masterstudiengang Wirtschaftsinformatik der Fachhochschule Vorarlberg vor. Es werden die Rahmenbedingungen der Lehrveranstaltung erläutert und die didaktischen Überlegungen sowie Zielsetzungen diskutiert. Besonderes Augenmerk wird auf die Vorteile des Blended Learning sowie die Bedeutung von Feedback gelegt. Anschließend werden die Inhalte, der Aufbau sowie die verwendeten Materialien und Tools beschrieben. Es wird gesondert auf den Feedbackprozess eingegangen. Abschließend erfolgt eine Bewertung des Lehrveranstaltungskonzepts anhand der Dimensionen technischer Ablauf, Engagement der Studierenden, Klausurerfolg und Lehrveranstaltungsevaluation. Auf dieser Basis werden mögliche Verbesserungen für die Zukunft abgeleitet. Insgesamt wird deutlich, dass der Flipped Classroom-Ansatz eine effektive Methode ist, die mit Standardtools umgesetzt werden kann und die den Lernerfolg und die Zufriedenheit der Studierenden fördert.
The main aims of this work are the validation of the developed process of gluing a single-mode optical fiber array with a photonic chip and the selection of a more suitable adhesive from the two adhesives being compared. An active alignment system was used for adjusting the two optical fiber arrays to a photonics chip. The gluing was done by two compared UV curable adhesives applied in the optical path. The insertion losses of glued coupling were measured and investigated at two discrete wavelengths 1310 nm and 1550 nm during temperature testing in the climatic chamber according to Telcordia GR_1209_Corei04 [3]. The measurement, investigation, and comparison of insertion losses of the glued coupling at the spectral band from 1530 nm to 1570 nm were done immediately after gluing process and after three temperature cycles in the climatic chamber with one month delay.
In this paper, a 256-channel, 10-GHz arrayed waveguide gratings demultiplexer for ultra-dense wavelength division multiplexing was designed using an in-house developed tool called AWG-Parameters. The AWG demultiplexer was designed for a central wavelength of 1550 nm and the structure was simulated in PHASAR tool from Optiwave. Two different AWG designs were developed and the influence of the design parameters on the AWG performance was studied.
Das Kreisgespräch
(2023)
In Bewegung kommen
(2023)
Das Modellprojekt „Caritas Care – Betreuung zuhause“ wurde 2012 in einer Kooperation der Caritas Schweiz und der Caritas Alba Iulia (Transsylvanien/Rumänien) ins Leben gerufen. Damit sollte ein Modell geschaffen werden, welches einerseits dem wachsenden Markt der „Betreuung zuhause“ in der Schweiz entgegenkommt, aber andererseits fairere Arbeitsbedingungen für die Betreuungspersonen vorsieht. Fairness sollte durch einen Versicherungsschutz der Arbeitskräfte, Weiterbildungsmöglichkeiten und ein Entgelt, das mit anderen Arbeitsverhältnissen vergleichbar ist, sowie dank klar abgegrenzter Arbeits-, Präsenz- und Freizeit erreicht werden. Die Umsetzung erfolgt folgendermaßen: Angestellte Betreuungs- und Pflegefachkräfte der Caritas Alba Iulia können für sechs Wochen bis zu drei Monaten in die Schweiz gehen, um dort in Privathaushalten hilfsbedürftige Menschen zu unterstützen (Live-in-Betreuungen). Sie werden während dieser Zeit von der Caritas Schweiz angestellt. Danach kehren die Betreuenden wieder in ihr Anstellungsverhältnis bei der Caritas Alba Iulia zurück. Es wird sozusagen Personal „verliehen“. Damit soll einem Verlust von qualifiziertem Betreuungs- und Pflegepersonal durch Abwanderung aus Rumänien entgegengewirkt werden. Im Rahmen des studiengangsübergreifenden, interdisziplinären Kontextstudiums der Masterstudiengänge der Fachhochschule Vorarlberg (Österreich) hat sich eine Gruppe Forschender zum Ziel gesetzt, dieses Modellprojekt forscherisch zu erkunden. Wir wollten wissen, wie dieses Live-in-Betreuungsangebot nach zehn Jahren Laufzeit funktioniert. Insbesondere interessierten uns die Erfahrungen der rumänischen Betreuer:innen und ihrer Angehörigen sowie der projektverantwortlichen Leitungspersonen in der Caritas Alba Iulia und der Caritas Schweiz. Im Rahmen einer Feldforschungswoche im Juli 2022 in Transsylvanien/Siebenbürgen wurden 28 formelle Interviews mit Projektverantwortlichen, Betreuern/Betreuerinnen und deren Angehörigen durchgeführt. Zusätzlich wurden Dokumente und Feldnotizen sowie Gedächtnisprotokolle von informellen Gesprächen mit Personen der extramuralen Einrichtungen in Rumänien in die Auswertung integriert. Die Auswertung erfolgte inhaltsanalytisch.
Organic acidurias (OAs), urea-cycle disorders (UCDs), and maple syrup urine disease (MSUD) belong to the category of intoxication-type inborn errors of metabolism (IT-IEM). Liver transplantation (LTx) is increasingly utilized in IT-IEM. However, its impact has been mainly focused on clinical outcome measures and rarely on health-related quality of life (HRQoL). Aim of the study was to investigate the impact of LTx on HrQoL in IT-IEMs. This single center prospective study involved 32 patients (15 OA, 11 UCD, 6 MSUD; median age at LTx 3.0 years, range 0.8–26.0). HRQoL was assessed pre/post transplantation by PedsQL-General Module 4.0 and by MetabQoL 1.0, a specifically designed tool for IT-IEM. PedsQL highlighted significant post-LTx improvements in total and physical functioning in both patients' and parents' scores. According to age at transplantation (≤3 vs. >3 years), younger patients showed higher post-LTx scores on Physical (p = 0.03), Social (p < 0.001), and Total (p =0.007) functioning. MetabQoL confirmed significant post-LTx changes in Total and Physical functioning in both patients and parents scores (p ≤ 0.009). Differently from PedsQL, MetabQoL Mental (patients p = 0.013, parents p = 0.03) and Social scores (patients p = 0.02, parents p = 0.012) were significantly higher post-LTx. Significant improvements (p = 0.001–0.04) were also detected both in self- and proxy-reports for almost all MetabQoL subscales. This study shows the importance of assessing the impact of transplantation on HrQoL, a meaningful outcome reflecting patients' wellbeing. LTx is associated with significant improvements of HrQol in both self- and parentreports. The comparison between PedsQL-GM and MetabQoL highlighted that MetabQoL demonstrated higher sensitivity in the assessment of diseasespecific domains than the generic PedsQL tool.
Demand-side management approaches that exploit the temporal flexibility of electric vehicles have attracted much attention in recent years due to the increasing market penetration. These demand-side management measures contribute to alleviating the burden on the power system, especially in distribution grids where bottlenecks are more prevalent. Electric vehicles can be defined as an attractive asset for distribution system operators, which have the potential to provide grid services if properly managed. In this thesis, first, a systematic investigation is conducted for two typically employed demand-side management methods reported in the literature: A voltage droop control-based approach and a market-driven approach. Then a control scheme of decentralized autonomous demand side management for electric vehicle charging scheduling which relies on a unidirectionally communicated grid-induced signal is proposed. In all the topics considered, the implications on the distribution grid operation are evaluated using a set of time series load flow simulations performed for representative Austrian distribution grids. Droop control mechanisms are discussed for electric vehicle charging control which requires no communication. The method provides an economically viable solution at all penetrations if electric vehicles charge at low nominal power rates. However, with the current market trends in residential charging equipment especially in the European context where most of the charging equipment is designed for 11 kW charging, the technical feasibility of the method, in the long run, is debatable. As electricity demand strongly correlates with energy prices, a linear optimization algorithm is proposed to minimize charging costs, which uses next-day market prices as the grid-induced incentive function under the assumption of perfect user predictions. The constraints on the state of charge guarantee the energy required for driving is delivered without failure. An average energy cost saving of 30% is realized at all penetrations. Nevertheless, the avalanche effect due to simultaneous charging during low price periods introduces new power peaks exceeding those of uncontrolled charging. This obstructs the grid-friendly integration of electric vehicles.
Background: Cardiovascular disease is the major cause of death worldwide. Although knowledge regarding diagnosing and treating cardiovascular disease has increased dramatically, secondary prevention remains insufficiently implemented due to failure among affected individuals to adhere to guideline recommendations. This has continued to lead to high morbidity and mortality rates. Involving patients in their healthcare and facilitating their active roles in their chronic disease management is an opportunity to meet the needs of the increasing number of cardio-vascular patients. However, simple recall of advice regarding a more preventive lifestyle does not affect sustainable behavioral lifestyle changes. We investigate the effect of plaque visualization combined with low-threshold daily lifestyle tasks using the smartphone app PreventiPlaque to evaluate change in cardiovascular risk profile. Methods: and study design: This randomized, controlled clinical trial includes 240 participants with ultrasound evidence of atherosclerotic plaque in one or both carotid arteries, defined as focal thickening of the vessel wall measuring 50% more than the regular vessel wall. A criterion for participation is access to a smartphone suitable for app usage. The participants are randomly assigned to an intervention or a control group. While both groups receive the standard of care, the intervention group has additional access to the PreventiPlaque app during the 12-month follow-up. The app includes daily tasks that promote a healthier lifestyle in the areas of smoking cessation, medication adherence, physical activity, and diet. The impact of plaque visualization and app use on the change in cardiovascular risk profile is assessed by SCORE2. Feasibility and effectiveness of the PreventiPlaque app are evaluated using standardized and validated measures for patient feedback.
The usage of data gathered for Industry 4.0 and smart factory scenarios continues to be a problem for companies of all sizes. This is often the case because they aim to start with complicated and time-intensive Machine Learning scenarios. This work evaluates the Process Capability Analysis (PCA) as a pragmatic, easy and quick way of leveraging the gathered machine data from the production process. The area of application considered is injection molding. After describing all the required domain knowledge, the paper presents an approach for a continuous analysis of all parts produced. Applying PCA results in multiple key performance indicators that allow for fast and comprehensible process monitoring. The corresponding visualizations provide the quality department with a tool to efficiently choose where and when quality checks need to be performed. The presented case study indicates the benefit of analyzing whole process data instead of considering only selected production samples. The use of machine data enables additional insights to be drawn about process stability and the associated product quality.
Tap or swipe
(2023)