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Interstitial photodynamic therapy (iPDT) treats malignant brain cancer cells by irradiation with low power laser light. The light is guided into the human body by diffuse emitting fibers. This study targets the light distribution of optical diffusers within the brain tissue. It was shown, that by submerging an optical diffuser into human brain phantom, its radiation profile measured in air converges towards a Gaussian distribution with increasing phantom depth. A camera method using digital averaging filters as well as an integrating sphere setup, both, smoothing the diffuser radiation profile were applied onto the evaluated diffuser.
Was ist zu tun?
(2019)
Zusammenfassung: Eine umfassende Literaturrecherche (Comprehensive Literature Search, CLS) bezeichnet eine umfangreiche und aufwändige Recherche mit dem Ziel, möglichst alle Studien zur Beantwortung einer zugrundeliegenden Forschungsfrage im Rahmen einer systematischen Übersichtsarbeit zu identifizieren. Konkrete Empfehlungen oder eine Definition des Begriffs CLS gibt es jedoch nicht. Der vorliegende Beitrag führt in eine Rahmung der CLS ein, stellt die damit einhergehenden Herausforderungen dar und weist auf methodische Implikationen sowie mögliche zukünftige Forschungsbereiche hin.
