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Wer wünscht ihn nicht: den intelligenten, effizienten und wirtschaftlichen Herstellungsprozess? Viele Firmen setzten aktuell auf die Digitalisierung und verbessern so die eigene sowie die mit externen Stellen vernetzte Produktion. Die Digitalisierung bringt einerseits Fortschritt, zeigt aber auch die zunehmende Komplexität der heutigen Produktionsnetzwerke auf. Zahlreiche Entscheidungen sind zu fällen, um einen effizienten und sicheren Austausch mit verschiedenen Betrieben zu gewährleisten.
Ein Blick auf vorhandene Modelle kann da weiterhelfen: Im Projekt i4Production des IBH-Labs KMUdigital haben Teams an drei Standorten in den drei Nachbarländern Deutschland (HTWG Konstanz), Österreich (FH Vorarlberg) und der Schweiz (NTB Buchs, RhySearch) an einer vernetzten Prozesslandschaft gearbeitet. In einem gemeinsamen, standardisierten Automatisierungskonzept wird in der international vernetzten Modellfabrik ein cyberphysisches System (CPS) in Form eines kundenindividualisierten Modellfahrzeuges produziert, das durch den Kunden in diversen Varianten zusammengestellt oder individuell konstruiert werden kann. Die dezentrale Produktion erlaubt eine Datenweitergabe über die Landesgrenzen in Echtzeit und bildet die Simulation eines länderübergreifenden Business-Eco-Systems ab.
Die Erkenntnisse des Projekts i4Production zeigen wie in kleineren und mittleren Unternehmen (KMU) eine verteilte Produktion, inklusive der Einbindung von Mitarbeitenden und Kunden in eine digitalisierte, hochautomatisierte und kundenindividuelle Produktion, organisiert werden kann.
Für Unternehmen wird diese Industrie 4.0-Prozesslandschaft als Modell für die eigene Fertigung in dem neu aufgebauten CNC Präzisionsfertigungslabor „Werkstatt4“ bei RhySearch öffentlich zur Verfügung gestellt. Die „Werkstatt4“ bietet KMU ein digitales Prozessumfeld, in dem getestet werden kann, mit welchen Maßnahmen der eingangs gestellte Wunsch zur optimierten Herstellung, seinen Weg in die Realität finden kann.
Im Folgenden stellen wir Ihnen das Konzept der internationalen Musterfabrik i4Production, die diversen Arbeitsschritte an den beteiligten Hochschulen sowie die wichtigsten Erkenntnisse für KMU der Bodenseeregion vor. Gerne unterstützen wir Sie bei der Gestaltung des Wandels hin zum Unternehmen 4.0: Sprechen Sie uns an.
Post-operative isoflurane has been observed to be present in the end-tidal breath of patients who have undergone major surgery, for several weeks after the surgical procedures. A major new noncontrolled, non-randomized, and open-label approved study will recruit patients undergoing various surgeries under different inhalation anaesthetics, with two key objectives, namely to record the washout characteristics following surgery, and to investigate the influence of a patient’s health and the duration and type of surgery on elimination. In preparation for this breath study using proton transfer reaction time-of-flight mass spectrometry (PTR-TOF-MS), it is important to identify first the analytical product ions that need to be monitored and under what operating conditions. In this first paper of this new research programme, we present extensive PTR-TOF-MS studies of three major
anaesthetics used worldwide, desflurane (CF3CHFOCHF2), sevoflurane ((CF3)2CHOCH2F), and isoflurane (CF3CHClOCHF2) and a fourth one, which is used less extensively, enflurane (CHF2OCF2CHFCl), but is of interest because it is an isomer of isoflurane. Product ions are identified as a function of reduced electric field (E/N) over the range of approximately 80 Td to 210 Td, and the effects of operating the drift tube under ‘normal’ or ‘humid’ conditions on the intensities of the product ions are presented. To aid in the analyses, density functional theory (DFT) calculations of the proton affinities and the gas-phase basicities of the anaesthetics have been determined. Calculated energies for the ion-molecule reaction pathways leading to key product ions, identified as ideal for monitoring the inhalation anaesthetics in breath with a high sensitivity and selectivity, are also presented.
For a given set of banks, how big can losses in bad economic or financial scenarios possibly get, and what are these bad scenarios? These are the two central questions of stress tests for banks and the banking system. Current stress tests select stress scenarios in a way which might leave aside many dangerous scenarios and thus create an illusion of safety; and which might consider highly implausible scenarios and thus trigger a false alarm. We show how to select scenarios systematically for a banking system in a context of multiple credit exposures. We demonstrate the application of our method in an example on the Spanish and Italian residential real estate exposures of European banks. Compared to the EBA 2016 stress test our method produces scenarios which are equally plausible as the EBA stress scenario but yield considerably worse system wide losses.
Real-time measurements of the differences in inhaled and exhaled, unlabeled and fully deuterated acetone concentration levels, at rest and during exercise, have been conducted using proton transfer reaction mass spectrometry. A novel approach to continuously differentiate between the inhaled and exhaled breath acetone concentration signals is used. This leads to unprecedented fine grained data of inhaled and exhaled concentrations. The experimental results obtained are compared with those predicted using a simple three compartment model that theoretically describes the influence of inhaled concentrations on exhaled breath concentrations for volatile organic compounds with high blood:air partition coefficients, and hence is appropriate for acetone. An agreement between the predicted and observed concentrations is obtained. Our results highlight that the influence of the upper airways cannot be neglected for volatiles with high blood:air partition coefficients, i.e. highly water soluble volatiles.
Blood flow and ventilatory flow strongly influence the concentrations of volatile organic compounds (VOCs) in exhaled breath. The physicochemical properties of a compound (e.g., water solubility) additionally determine if the concentration of the compound in breath reflects the alveolar concentration, the concentration in the upper airways, or a mixture of both. Mathematical modeling based on mass balance equations helps to understand how measured breath concentrations are related to their corresponding blood concentrations and physiological parameters, such as metabolic rates and endogenous production rates. In addition, the influence of inhaled compounds on their exhaled concentrations can be quantified and appropriate correction formulas can be derived. Isoprene and acetone, two endogenous VOCs with very different water solubility, have been modeled to explain the essential features of their behavior in breath. This chapter introduces the theory of physiological modeling of exhaled VOCs, with examples of isoprene and acetone.
With the emergence of the recent Industry 4.0 movement, data integration is now also being driven along the production line, made possible primarily by the use of established concepts of intelligent supply chains, such as the digital avatars. Digital avatars – sometimes also called Digital Twins or more broadly Cyber-Physical Systems (CPS) – are already successfully used in holistic systems for intelligent transport ecosystems, similar to the use of Big Data and artificial intelligence technologies interwoven with modern production and supply chains. The goal of this paper is to describe how data from interwoven, autonomous and intelligent supply chains can be integrated into the diverse data ecosystems of the Industry 4.0, influenced by a multitude of data exchange formats and varied data schemas. In this paper, we describe how a framework for supporting SMEs was established in the Lake Constance region and describe a demonstrator sprung from the framework. The demonstrator project’s goal is to exhibit and compare two different approaches towards optimisation of manufacturing lines. The first approach is based upon static optimisation of production demand, i.e. exact or heuristic algorithms are used to plan and optimise the assignment of orders to individual machines. In the second scenario, we use real-time situational awareness – implemented as digital avatar – to assign local intelligence to jobs and raw materials in order to compare the results to the traditional planning methods of scenario one. The results are generated using event-discrete simulation and are compared to common (heuristic) job scheduling algorithms.
ÖMG Conference 2019
(2019)
On the extension of digital ecosystems for SCM and customs with distributed ledger technologies
(2019)
Global supply chains represent the backbone of the modern manufacturing industry. Planning of global supply chains still represents a major hurdle, mainly because of the high complexity and unforeseen disruptions that have to be mastered for meeting the different logistics windows in a globally distributed production environment. Trust in supply chains is an additional challenge. A major – albeit sometimes overlooked - part of Supply Chain Management (SCM) is the management and integration of customs processes, clearing of tariffs, (re-)billing of customers, and fulfilling other legal requirements related to crossing borders, ranging from environmental standards over goods inspection to general paper work. With the exception of work offered by the World Customs Organization (WCO) the issue of customs and blockchain is still underrepresented in research and practice. In this paper, we look at innovations that drive the current ICTenabled SCM research and how these can be combined with smart customs management. After a literature review and introduction to the state-of-the-art, we list potential trust-based innovations for SCM and customs in digital business ecosystems. Based upon the innovations we also describe a requirements analysis of existing distributed ledger technologies (requirements for system layout, system configuration, system governance). A description of the prototype for the Lake Constance region – on which we are currently working – concludes the paper.
To create a map of an unknown area, autonomous robots must follow a strategy to explore the area without knowing the optimal paths to reduce the time needed to map the whole area. To reduce the time to accomplish this task, multiple robots can work together to create a map in a more efficient way. However, without proper coordination, the time a team of autonomous robots needs to explore the unknown area can exceed the time needed by a single robot. To counteract the challenges, a shared infrastructure is needed which extracts useful information for the individual robots out of the shared information of all robots so the exploration can be coordinated. These measures introduce new challenges to the system, concerning the load of the communication infrastructure as well as the overall task of exploring and mapping becoming dependent on the correct communication and robustness of the shared team infrastructure. Therefore, the amount of communication and dependency of each individual robot of the rest of the other robots of the team must be reduced to ensure that the robots can continue working even if the communication with the shared infrastructure fails.
Mobility choices - an instrument for precise automatized travel behavior detection & analysis
(2021)
With Cloud Computing and multi-core CPUs parallel computing resources are becoming more and more affordable and commonly available. Parallel programming should as well be easily accessible for everyone. Unfortunately, existing frameworks and systems are powerful but often very complex to use for anyone who lacks the knowledge about underlying concepts. This paper introduces a software framework and execution environment whose objective is to provide a system which should be easily usable for everyone who could benefit from parallel computing. Some real-world examples are presented with an explanation of all the steps that are necessary for computing in a parallel and distributed manner.