Refine
Year of publication
- 2023 (47) (remove)
Document Type
- Article (47) (remove)
Institute
- Wirtschaft (16)
- Forschungszentrum Mikrotechnik (10)
- Soziales & Gesundheit (8)
- Forschungszentrum Business Informatics (4)
- Forschungszentrum Human Centred Technologies (4)
- Forschungszentrum Energie (3)
- Forschung (2)
- Josef Ressel Zentrum für Intelligente Thermische Energiesysteme (2)
- Forschungsgruppe Empirische Sozialwissenschaften (1)
- Gestaltung (1)
- Josef Ressel Zentrum für Robuste Entscheidungen (1)
Keywords
- Schreibdidaktik (3)
- Business Analytics (2)
- Controlling (2)
- Excel (2)
- Prognose (2)
- Zeitreihenanalyse (2)
- AWG (1)
- AWG-spectrometer (1)
- Akademisierung (1)
- Anthropocentrism (1)
Pooled data from published reports on infants with clinically diagnosed vitamin B12 (B12) deficiency were analyzed with the purpose of describing the presentation, diagnostic approaches, and risk factors for the condition to inform prevention strategies. An electronic (PubMed database) and manual literature search following the PRISMA approach was conducted (preregistration with the Open Science Framework, accessed on 15 February 2023). Data were described and analyzed using correlation analyses, Chi-square tests, ANOVAs, and regression analyses, and 102 publications (292 cases) were analyzed. The mean age at first symptoms (anemia, various neurological symptoms) was four months; the mean time to diagnosis was 2.6 months. Maternal B12 at diagnosis, exclusive breastfeeding, and a maternal diet low in B12 predicted infant B12, methylmalonic acid, and total homocysteine. Infant B12 deficiency is still not easily diagnosed. Methylmalonic acid and total homocysteine are useful diagnostic parameters in addition to B12 levels. Since maternal B12 status predicts infant B12 status, it would probably be advantageous to target women in early pregnancy or even preconceptionally to prevent infant B12 deficiency, rather than to rely on newborn screening that often does not reliably identify high-risk children.
Redundanz und Varietät
(2023)
Ausrechnen oder aushandeln?
(2023)
Das Kreisgespräch
(2023)
Formen des Dialogs
(2023)
Die persönliche Black-Box
(2023)
Der Schlüssel zur Zukunft
(2023)
Background: Cardiovascular disease is the major cause of death worldwide. Although knowledge regarding diagnosing and treating cardiovascular disease has increased dramatically, secondary prevention remains insufficiently implemented due to failure among affected individuals to adhere to guideline recommendations. This has continued to lead to high morbidity and mortality rates. Involving patients in their healthcare and facilitating their active roles in their chronic disease management is an opportunity to meet the needs of the increasing number of cardio-vascular patients. However, simple recall of advice regarding a more preventive lifestyle does not affect sustainable behavioral lifestyle changes. We investigate the effect of plaque visualization combined with low-threshold daily lifestyle tasks using the smartphone app PreventiPlaque to evaluate change in cardiovascular risk profile. Methods: and study design: This randomized, controlled clinical trial includes 240 participants with ultrasound evidence of atherosclerotic plaque in one or both carotid arteries, defined as focal thickening of the vessel wall measuring 50% more than the regular vessel wall. A criterion for participation is access to a smartphone suitable for app usage. The participants are randomly assigned to an intervention or a control group. While both groups receive the standard of care, the intervention group has additional access to the PreventiPlaque app during the 12-month follow-up. The app includes daily tasks that promote a healthier lifestyle in the areas of smoking cessation, medication adherence, physical activity, and diet. The impact of plaque visualization and app use on the change in cardiovascular risk profile is assessed by SCORE2. Feasibility and effectiveness of the PreventiPlaque app are evaluated using standardized and validated measures for patient feedback.